Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Nephrotic syndrome
ADR ID BADD_A03027
ADR Hierarchy
20      Renal and urinary disorders
20.05      Nephropathies
20.05.01      Glomerulonephritis and nephrotic syndrome
20.05.01.002      Nephrotic syndrome
Description A disorder characterized by symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction. [CTCAE] Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA. [MeSH]
MedDRA Code 10029164
MeSH ID D009401; D009404; D009404
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Nephrosis | Nephrosis osmotic | Nephrotic syndrome | Nephrotic syndrome in diseases classified elsewhere | Nephrotic syndrome with lesion of membranoproliferative glomerulonephritis | Nephrotic syndrome with lesion of membranous glomerulonephritis | Nephrotic syndrome with lesion of minimal change glomerulonephritis | Nephrotic syndrome with lesion of proliferative glomerulonephritis | Nephrotic syndrome with other pathological lesion in kidney | Nephrotic syndrome with other specified pathological lesion in kidney | Nephrotic syndrome with unspecified pathological lesion in kidney | Syndrome nephrotic | Nephrotic syndrome worsened | Steroid-resistant nephrotic syndrome | Nephroses
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00014Abiraterone--
BADD_D00029Acetyl sulfisoxazole--
BADD_D00049Agalsidase beta--
BADD_D00066Alendronic acid0.000202%
BADD_D00071Alglucosidase alfa--
BADD_D00121Amlodipine0.000077%
BADD_D00129Amoxicillin0.000020%
BADD_D00132Amphotericin b--
BADD_D00139Anagrelide0.000533%
BADD_D00151Apixaban--
BADD_D00165Aripiprazole--
BADD_D00191Auranofin--
BADD_D00193Axitinib0.005861%
BADD_D00203Azithromycin--
BADD_D00271Bicalutamide0.006444%
BADD_D00330Cabozantinib0.001332%
BADD_D00354Captopril--
BADD_D00356Carbamazepine0.000842%
BADD_D00367Carfilzomib0.000533%
BADD_D00410Celecoxib--
BADD_D00416Certolizumab pegol--
BADD_D00424Cevimeline--
BADD_D00425Cevimeline hydrochloride--
BADD_D00429Chlorambucil--
BADD_D00463Cidofovir--
BADD_D00474Cisplatin0.000139%
BADD_D00480Clarithromycin0.000823%
BADD_D00504Clopidogrel0.000294%
BADD_D00508Clostridium tetani toxoid immune globulin (human)--
BADD_D00511Clozapine--
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